Zope.org - Python For .NET: "Python for .NET
Python for .NET is a near-seamless integration of the Python runtime with the .NET Common Language Runtime (CLR). It lets you script and build applications in Python, using CLR services and components written in any language that targets the CLR (C#, Managed C++, VB.NET, etc.).
The package is open source, released under the ZPL. It is currently in beta, nearly feature-complete and usable for real-world applications. "